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Small (1)metronidazole topical will increase the level or impact of ethanol by decreasing metabolism. Minimal/Significance Unidentified. Disulfiram-like response with oral metronidazole and alcohol; less likely to occur with vaginal administration due to minimal absorption
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Recognised or Earlier unrecognized vaginal candidiasis may well current much more prominent signs and symptoms all through therapy with metronidazole vaginal gel. About 6-ten% of clients taken care of with METROGELVAGINAL developed symptomatic Candida vaginitis throughout or immediately soon after therapy.
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Disulfiram-like response to Liquor has actually been described with oral metronidazole, Consequently the opportunity of such a reaction transpiring even though on metronidazole vaginal gel therapy can't be excluded.
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Whilst metronidazole has revealed mutagenic activity jne toto in quite a few in vitro assay devices, scientific tests in mammals (in vivo) have did not exhibit a potential for genetic injury.
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Usage of cimetidine with oral metronidazole may jnetoto perhaps extend the fifty percent-daily life and decrease plasma clearance of metronidazole.
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